Selected publications
Positioning and reversible suppression of CCR7+ dendritic cells in perivascular tumor niches shape cancer immunity
Zitti B, Duval F, Wirapati P, (...), Böttcher J, Weissleder R, Pittet MJ
Immunity – 2026
Convergent inducers and effectors of T cell paralysis in the tumour microenvironment
Hanahan D, Michielin O, Pittet MJ
Zitti B, Duval F, Wirapati P, (...), Böttcher J, Weissleder R, Pittet MJ
Immunity – 2026
Convergent inducers and effectors of T cell paralysis in the tumour microenvironment
Hanahan D, Michielin O, Pittet MJ
Nature Reviews Cancer – 2025
Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy
Wang C, Zeng Qm Gül ZM, (...) Simonetta F, Pittet MJ, Scheiermann C
Cell – 2024
CXCL9:SPP1 macrophage polarity identifies a network of cellular programs that control human cancers
Bill R, Wirapati P, Messemaker M, (...), Pai SI, Sade-Feldman M, Pittet MJ
Science – 2023
A neutrophil response linked to tumor control in immunotherapy
Gungabeesoon J, Gort-Freitas NA, Kiss M, (...), Weissleder R, Klein AM, Pittet MJ
Cell – 2023
Dendritic cells as shepherds of T cell immunity in cancer
Pittet MJ, Di Pilato M, Garris C, Mempel TR
Immunity – 2023
Dendritic cells direct circadian anti-tumour immune responses
Wang C, Barnoud C, Cenerenti M, (...), Pittet MJ, Jandus C, Scheiermann C
Nature – 2023
Clinical relevance of tumour-associated macrophages
Pittet MJ, Michielin O, Migliorini D
Nature Reviews Clinical Oncology – 2022
CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment
Di Pilato M, Kfuri-Rubens R, Pruessmann JN, (...), Kobold S, Pittet MJ, Mempel TR
Cell – 2021
Resident Kupffer cells and neutrophils drive liver toxicity in cancer immunotherapy
Siwicki M, Gort-Freitas NA, Messemaker M, (...), Weissleder R, Klein AM, Pittet MJ
Science Immunology – 2021
Tumor-infiltrating dendritic cell states are conserved across solid human cancers
Gerhard GM, Bill R, Messemaker M, Klein AM, Pittet MJ
The Journal of Experimental Medicine – 2021
Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species
Zilionis R, Engblom C, Pfirschke C, (...), Levantini E, Pittet MJ, Klein AM
Immunity – 2019
Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12
Garris CS, Arlauckas SP, Kohler RH, (...), Zippelius A, Weissleder R, Pittet MJ
Immunity – 2018
Recording the wild lives of immune cells
Pittet MJ, Garris CS, Arlauckas SP, Weissleder R
Science Immunology – 2018
Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils
Engblom C, Pfirschke C, Zilionis R, (...), Scadden DT, Weissleder R, Pittet MJ
Science – 2017
In vivo imaging reveals a tumor-associated macrophage-mediated resistance pathway in anti-PD-1 therapy
Arlauckas SP, Garris CS, Kohler RH, (...), Anthony RM, Weissleder R, Pittet MJ
Science Translational Medicine – 2017
The role of myeloid cells in cancer therapies
Engblom C, Pfirschke C, Pittet MJ
Nature Reviews Cancer – 2016
SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactions
Pucci F, Garris C, Lai CP, (...), Mempel TR, Weissleder R, Pittet MJ
Science – 2016
Immunogenic chemotherapy sensitizes tumors to checkpoint blockade therapy
Pfirschke C, Engblom C, Rickelt S, (...), Zitvogel L, Weissleder R, Pittet MJ
Immunity – 2016
Origins of tumor-associated macrophages and neutrophils
Cortez-Retamozo V, Etzrodt M, Newton A, (...), Swirski FK, Weissleder R, Pittet MJ
PNAS – 2012
Intravital imaging
Pittet MJ, Weissleder R
Cell – 2011
Identification of splenic reservoir monocytes and their deployment to inflammatory sites
Swirski FK, Nahrendorf M, Etzrodt M, (...), Libby P, Weissleder R, Pittet MJ
Science – 2009
Imaging in the era of molecular oncology
Weissleder R, Pittet MJ
Nature – 2008
The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions
Nahrendorf M, Swirski FK, Aikawa E, (...), Libby P, Weissleder R, Pittet MJ
The Journal of Experimental Medicine – 2007
Ly6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata
Swirski FK, Libby P, Aikawa E, (...), Luscinskas FW, Weissleder R, Pittet MJ
The Journal of Clinical Investigation – 2007
Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy
Wang C, Zeng Qm Gül ZM, (...) Simonetta F, Pittet MJ, Scheiermann C
Cell – 2024
CXCL9:SPP1 macrophage polarity identifies a network of cellular programs that control human cancers
Bill R, Wirapati P, Messemaker M, (...), Pai SI, Sade-Feldman M, Pittet MJ
Science – 2023
A neutrophil response linked to tumor control in immunotherapy
Gungabeesoon J, Gort-Freitas NA, Kiss M, (...), Weissleder R, Klein AM, Pittet MJ
Cell – 2023
Dendritic cells as shepherds of T cell immunity in cancer
Pittet MJ, Di Pilato M, Garris C, Mempel TR
Immunity – 2023
Dendritic cells direct circadian anti-tumour immune responses
Wang C, Barnoud C, Cenerenti M, (...), Pittet MJ, Jandus C, Scheiermann C
Nature – 2023
Clinical relevance of tumour-associated macrophages
Pittet MJ, Michielin O, Migliorini D
Nature Reviews Clinical Oncology – 2022
CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment
Di Pilato M, Kfuri-Rubens R, Pruessmann JN, (...), Kobold S, Pittet MJ, Mempel TR
Cell – 2021
Resident Kupffer cells and neutrophils drive liver toxicity in cancer immunotherapy
Siwicki M, Gort-Freitas NA, Messemaker M, (...), Weissleder R, Klein AM, Pittet MJ
Science Immunology – 2021
Tumor-infiltrating dendritic cell states are conserved across solid human cancers
Gerhard GM, Bill R, Messemaker M, Klein AM, Pittet MJ
The Journal of Experimental Medicine – 2021
Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species
Zilionis R, Engblom C, Pfirschke C, (...), Levantini E, Pittet MJ, Klein AM
Immunity – 2019
Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12
Garris CS, Arlauckas SP, Kohler RH, (...), Zippelius A, Weissleder R, Pittet MJ
Immunity – 2018
Recording the wild lives of immune cells
Pittet MJ, Garris CS, Arlauckas SP, Weissleder R
Science Immunology – 2018
Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils
Engblom C, Pfirschke C, Zilionis R, (...), Scadden DT, Weissleder R, Pittet MJ
Science – 2017
In vivo imaging reveals a tumor-associated macrophage-mediated resistance pathway in anti-PD-1 therapy
Arlauckas SP, Garris CS, Kohler RH, (...), Anthony RM, Weissleder R, Pittet MJ
Science Translational Medicine – 2017
The role of myeloid cells in cancer therapies
Engblom C, Pfirschke C, Pittet MJ
Nature Reviews Cancer – 2016
SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactions
Pucci F, Garris C, Lai CP, (...), Mempel TR, Weissleder R, Pittet MJ
Science – 2016
Immunogenic chemotherapy sensitizes tumors to checkpoint blockade therapy
Pfirschke C, Engblom C, Rickelt S, (...), Zitvogel L, Weissleder R, Pittet MJ
Immunity – 2016
Origins of tumor-associated macrophages and neutrophils
Cortez-Retamozo V, Etzrodt M, Newton A, (...), Swirski FK, Weissleder R, Pittet MJ
PNAS – 2012
Intravital imaging
Pittet MJ, Weissleder R
Cell – 2011
Identification of splenic reservoir monocytes and their deployment to inflammatory sites
Swirski FK, Nahrendorf M, Etzrodt M, (...), Libby P, Weissleder R, Pittet MJ
Science – 2009
Imaging in the era of molecular oncology
Weissleder R, Pittet MJ
Nature – 2008
The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions
Nahrendorf M, Swirski FK, Aikawa E, (...), Libby P, Weissleder R, Pittet MJ
The Journal of Experimental Medicine – 2007
Ly6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata
Swirski FK, Libby P, Aikawa E, (...), Luscinskas FW, Weissleder R, Pittet MJ
The Journal of Clinical Investigation – 2007